Synthesis of Pyridazine Derivatives as Herbicides
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چکیده
منابع مشابه
Synthesis of Some New Pyridazine Derivatives for Anti-HAV Evaluation.
4-(2-(4-Halophenyl)hydrazinyl)-6-phenylpyridazin-3(2H)-ones 1a,b were prepared and treated with phosphorus oxychloride, phosphorus pentasulphide and ethyl chloroformate to give the corresponding chloropyridazine, pyridazinethione, oxazolopyridazine derivatives 2-4, respectively. Compound 2 reacted with hydrazine hydrate to afford hydrazinylpyridazine 7. The reaction of 4-(2-(4-chlorophenyl)hydr...
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Herein, we report the synthesis and pharmacological properties of several series of pyridazine and pyridazinone derivatives. All the synthesized compounds were tested, in vivo, for their anti-inflammatory and ulcerogenic properties against indomethacin, as a reference compound. Compounds 4a and 9d have shown a potent anti-inflammatory activity more than indomethacin with rapid onset of action a...
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Cancer is not just one disease, but a large group of almost one hundred diseases. Its two main characteristics are uncontrolled growth of the cells in the human body and the ability of these cells to migrate from the original site and spread to distant sites. If the spread is not controlled, cancer can result in death. There has been continuous progress in the development of therapy for cancer....
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Coupling of compound 1 with diazotized aromatic amines in ethanol afforded the arylhydrazones 3a,b. Fusion of 3a,b with active methylene derivatives 4a,b afforded the pyridazine derivatives 6a–d. Also, when compounds 6b,c were reacted with elemental sulphur afforded the thienopyridazine derivatives 7a,b. Treatment of compound 8 with hydrazine hydrate produced pyrazolopyridine derivative 9. Pyri...
متن کاملSynthesis and antiviral activities of 3-aralkylthiomethylimidazo[1,2-b]pyridazine derivatives.
The synthesis of novel substituted 3-aralkylthiomethylimidazo[1,2-b]pyridazines is reported. All of the synthesized compounds are devoid of antiviral activity against the replication of human immunodeficiency virus. However, compounds 6-chloro-8-methyl-3-phenethylthioimidazo[1,2-b]pyridazine and 6-chloro-2-methyl-3-phenethylthioimidazo[1,2-b]pyridazine are potent inhibitors of the replication o...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1963
ISSN: 1881-1280,0002-1369
DOI: 10.1271/bbb1961.27.653